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AMD Instinct MI250X~58 tok/s (Q4)

unsloth/Qwen3.5-397B-A17B-GGUF speed on AMD Instinct MI250X

Quantization-specific throughput and VRAM requirements for unsloth/Qwen3.5-397B-A17B-GGUF running on AMD Instinct MI250X.

Speed Snapshot

Topline estimate from compatibility data

Modelunsloth/Qwen3.5-397B-A17B-GGUF

GPUAMD Instinct MI250X

Q4 speed58 tok/s

Q4 VRAM required222GB

Data Source

Calculation and benchmark status

Speed values come from the compatibility dataset (`estimatedTokensPerSec`) and are sorted by quantization.

For full verdict logic and alternate GPUs, see the canonical compatibility page.

Quantization Speed Table

Quantization	VRAM needed	VRAM available	Speed	Verdict
Q4	222GB	128GB	58 tok/s	❌ Not recommended
Q8	444GB	128GB	42 tok/s	❌ Not recommended
FP16	888GB	128GB	22 tok/s	❌ Not recommended