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  4. Speed on AMD Instinct MI250X
AMD Instinct MI250X~92 tok/s (Q4)

Qwen/Qwen2.5-72B-Instruct speed on AMD Instinct MI250X

Quantization-specific throughput and VRAM requirements for Qwen/Qwen2.5-72B-Instruct running on AMD Instinct MI250X.

Speed Snapshot
Topline estimate from compatibility data
ModelQwen/Qwen2.5-72B-Instruct
GPUAMD Instinct MI250X
Q4 speed92 tok/s
Q4 VRAM required35GB
Data Source
Calculation and benchmark status

Speed values come from the compatibility dataset (`estimatedTokensPerSec`) and are sorted by quantization.

For full verdict logic and alternate GPUs, see the canonical compatibility page.

Open full compatibility report

Quantization Speed Table

QuantizationVRAM neededVRAM availableSpeedVerdict
Q435GB128GB92 tok/s✅ Fits
Q870GB128GB67 tok/s✅ Fits
FP16141GB128GB33 tok/s❌ Not recommended
Back to Qwen/Qwen2.5-72B-InstructQ4 requirement pageFull compatibility breakdown