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Can RTX 4090 run Qwen/Qwen3-Next-80B-A3B-Instruct?

Q4 not recommended24GB VRAM availableRequires 39GB+

RTX 4090 does not meet the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-Next-80B-A3B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

RTX 4090 lacks sufficient VRAM for comfortable Qwen/Qwen3-Next-80B-A3B-Instruct operation with Q4 quantization.

Your 24GB GPU is 15GB short of the 39GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q439GB24GB36.40 tok/s❌ Not recommended
Q878GB24GB27.37 tok/s❌ Not recommended
FP16156GB24GB13.50 tok/s❌ Not recommended

Best current price

RTX 4090
$1,599.00 on Amazon
Check Price

Suitable alternatives

AMD Instinct MI300X
192GB
167.62 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
139.18 tok/s
Price: —
AMD Instinct MI300X
192GB
117.41 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
97.60 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
97.49 tok/s
Price: —

More questions

RTX 4090 specs & pricingFull guide for Qwen/Qwen3-Next-80B-A3B-InstructQwen/Qwen3-Next-80B-A3B-Instruct speed on RTX 4090Qwen/Qwen3-Next-80B-A3B-Instruct Q4 requirements