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Can RTX 4080 Super run Qwen/Qwen3.5-397B-A17B?

Q4 not recommended16GB VRAM availableRequires 222GB+

RTX 4080 Super does not meet the minimum VRAM requirement for Q4 inference of Qwen/Qwen3.5-397B-A17B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

RTX 4080 Super lacks sufficient VRAM for comfortable Qwen/Qwen3.5-397B-A17B operation with Q4 quantization.

Your 16GB GPU is 206GB short of the 222GB minimum.

Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q4222GB16GB16.18 tok/s❌ Not recommended
Q8444GB16GB9.78 tok/s❌ Not recommended
FP16888GB16GB5.71 tok/s❌ Not recommended

Suitable alternatives

No alternative GPUs with verified compatibility yet. Expand the compatibility import to surface more cards.

More questions

RTX 4080 Super specs & pricingFull guide for Qwen/Qwen3.5-397B-A17BQwen/Qwen3.5-397B-A17B speed on RTX 4080 SuperQwen/Qwen3.5-397B-A17B Q4 requirements