NVIDIA H200 SXM 141GB meets the minimum VRAM requirement for Q4 inference of mistralai/Mixtral-8x22B-Instruct-v0.1. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
NVIDIA H200 SXM 141GB can run mistralai/Mixtral-8x22B-Instruct-v0.1 with Q4 quantization. At approximately 187 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 72GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 69GB | 141GB | 186.56 tok/s | ✅ Fits comfortably |
| Q8 | 138GB | 141GB | 126.91 tok/s | ✅ Fits comfortably |
| FP16 | 275GB | 141GB | 63.71 tok/s | ❌ Not recommended |