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Can AMD Instinct MI300X run Qwen/Qwen3-8B-Base?

Runs Q4192GB VRAM availableRequires 4GB+

AMD Instinct MI300X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen3-8B-Base. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI300X can run Qwen/Qwen3-8B-Base with Q4 quantization. At approximately 774 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 188GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q44GB192GB773.50 tok/s✅ Fits comfortably
Q89GB192GB507.36 tok/s✅ Fits comfortably
FP1617GB192GB299.17 tok/s✅ Fits comfortably

Suitable alternatives

NVIDIA H200 SXM 141GB
141GB
702.66 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
506.27 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
489.37 tok/s
Price: —
AMD Instinct MI250X
128GB
486.86 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
371.37 tok/s
Price: —

More questions

AMD Instinct MI300X specs & pricingFull guide for Qwen/Qwen3-8B-BaseQwen/Qwen3-8B-Base speed on AMD Instinct MI300XQwen/Qwen3-8B-Base Q4 requirements