AMD Instinct MI250X does not meet the minimum VRAM requirement for Q4 inference of Qwen/Qwen3.5-397B-A17B. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI250X lacks sufficient VRAM for comfortable Qwen/Qwen3.5-397B-A17B operation with Q4 quantization.
Your 128GB GPU is 94GB short of the 222GB minimum.
Options: (1) Try Q2 or Q3 quantization for lower VRAM requirements, (2) Consider cloud GPU rental, (3) Upgrade to a GPU with at least 16GB VRAM.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 222GB | 128GB | 58.14 tok/s | ❌ Not recommended |
| Q8 | 444GB | 128GB | 36.15 tok/s | ❌ Not recommended |
| FP16 | 888GB | 128GB | 20.02 tok/s | ❌ Not recommended |
No alternative GPUs with verified compatibility yet. Expand the compatibility import to surface more cards.