AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of Qwen/Qwen2.5-14B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI250X can run Qwen/Qwen2.5-14B-Instruct with Q4 quantization. At approximately 350 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 121GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 7GB | 128GB | 350.33 tok/s | ✅ Fits comfortably |
| Q8 | 14GB | 128GB | 275.41 tok/s | ✅ Fits comfortably |
| FP16 | 29GB | 128GB | 130.37 tok/s | ✅ Fits comfortably |