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Can AMD Instinct MI250X run meta-llama/Llama-3.3-70B-Instruct?

Runs Q4128GB VRAM availableRequires 34GB+

AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of meta-llama/Llama-3.3-70B-Instruct. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.

What this means for you

AMD Instinct MI250X can run meta-llama/Llama-3.3-70B-Instruct with Q4 quantization. At approximately 105 tokens/second, you can expect Excellent speed - conversational response times under 1 second.

You have 94GB headroom, which is sufficient for system overhead and smooth operation.

Quantization breakdown

QuantizationVRAM neededVRAM availableEstimated speedVerdict
Q434GB128GB104.92 tok/s✅ Fits comfortably
Q869GB128GB65.44 tok/s✅ Fits comfortably
FP16138GB128GB39.38 tok/s❌ Not recommended

Suitable alternatives

AMD Instinct MI300X
192GB
150.43 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
148.16 tok/s
Price: —
AMD Instinct MI300X
192GB
116.28 tok/s
Price: —
NVIDIA H100 SXM5 80GB
80GB
90.38 tok/s
Price: —
NVIDIA H200 SXM 141GB
141GB
87.56 tok/s
Price: —

More questions

AMD Instinct MI250X specs & pricingFull guide for meta-llama/Llama-3.3-70B-Instructmeta-llama/Llama-3.3-70B-Instruct speed on AMD Instinct MI250Xmeta-llama/Llama-3.3-70B-Instruct Q4 requirements