AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of lmstudio-community/Qwen3-4B-Thinking-2507-MLX-6bit. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI250X can run lmstudio-community/Qwen3-4B-Thinking-2507-MLX-6bit with Q4 quantization. At approximately 516 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 126GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 2GB | 128GB | 515.66 tok/s | ✅ Fits comfortably |
| Q8 | 4GB | 128GB | 366.14 tok/s | ✅ Fits comfortably |
| FP16 | 9GB | 128GB | 184.57 tok/s | ✅ Fits comfortably |