AMD Instinct MI250X meets the minimum VRAM requirement for Q4 inference of deepseek-ai/DeepSeek-V3.1. Review the quantization breakdown below to see how higher precision settings impact VRAM and throughput.
AMD Instinct MI250X can run deepseek-ai/DeepSeek-V3.1 with Q4 quantization. At approximately 524 tokens/second, you can expect Excellent speed - conversational response times under 1 second.
You have 124GB headroom, which is sufficient for system overhead and smooth operation.
| Quantization | VRAM needed | VRAM available | Estimated speed | Verdict |
|---|---|---|---|---|
| Q4 | 4GB | 128GB | 524.05 tok/s | ✅ Fits comfortably |
| Q8 | 7GB | 128GB | 329.85 tok/s | ✅ Fits comfortably |
| FP16 | 15GB | 128GB | 184.82 tok/s | ✅ Fits comfortably |